Real-time, Automated Volume Color Doppler Quantification Improves the Measurement Accuracy of Chronic Mitral Regurgitation

Dr. Jose L. Zamorano, Director of the Cardiovascular Institute at the University Clinic in Madrid, Spain discusses the benefits of automated 3D imaging and measurement tools for the assessment of mitral regurgitation using the ACUSON SC2000™ ultrasound system.

It is estimated* that at least six million individuals in Europe and North America are thought to have some degree of mitral regurgitation. This represents a substantial caseload for echocardiography lab across these regions.


A sophisticated and widely used method to quantify mitral regurgitation is the measurement of the blood flow jet of the vena contracta using the proximal isovelocity surface area (PISA) of the jet. Based on 2D echo datasets, it measures the cross-section of the jet, but makes certain assumptions about the symmetry of flow.

The PISA, however, is often not symmetric or spherical. With 3D techniques, cardiologists can now look at the flow in its real shape, in all three dimensions. Dr. Zamorano uses eSie PISA™ quantification tool to measure the true PISA from volume color Doppler data.

Semi-automated measurements improve the workflow and help to reduce user variability. The Siemens unique eSie PISA software computes the status of PISA and the effective regurgitant orifice area (EROA), and the simple workflow delivers measurements within seconds.

* SWISS MED WKLY 2010; 140 (3–4): 36–43. Lancet 2009 Apr 18; 373 (9672): 1382-94.

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